Former President John Mahama, has described as "heartwarming to learn of the World Health Organization's (WHO) approval of a malaria vaccine after years of trial".
Mr. Mahama, was full of praise for officials of the global health body led by Dr. Tedros Adhanom Ghebreyesus.
The ex-President, who is known for his disease diplomacy, particularly the eradication of global pandemics such as HIV/AIDs and the Ebola virus, during his tenure in office, also commended one Dr. Vasee Moorthy and his team at the WHO whom he said, responded favourably to Ghana's expression of interest in the malaria vaccine programme in 2016.
The 2020 flag bearer of the main opposition National Democratic Congress (NDC), said in a Facebook comment yesterday that "It is refreshing and promising to learn that our expression of interest in 2016 to the WHO and active participation in the Malaria vaccine pilot programme has led to the approval of the vaccine to be deployed in sub-Saharan Africa and other malaria-endemic regions".
"I am elated at the prospect of vaccinating millions of African children who will be saved from avoidable deaths as a result of this scientific and public health breakthrough.
"Thanks to Dr.Vasee Moorthy and his team at the World Health Organization, who responded favourably to Ghana's expression of interest in the malaria vaccine programme in 2016.
"Congratulations to the WHO, Ghana's Technical Working Group and the governments and people of Malawi and Kenya, who joined us in the successful pilot immunization programme.
"As Dr. Tedros Adhanom Ghebreyesus, the Director-General of the WHO, said, this is, 'a historic moment'", Mr. Mahama added.
The WHO is recommending widespread use of the RTS,S/AS01 (RTS,S) malaria vaccine among children in sub-Saharan Africa and in other regions with moderate to high P. falciparum malaria transmission.
The recommendation is based on results from an ongoing pilot programme in Ghana, Kenya and Malawi that has reached more than 800, 000 children since 2019.
"This is a historic moment. The long-awaited malaria vaccine for children is a breakthrough for science, child health and malaria control," said WHO Director-General. "Using this vaccine on top of existing tools to prevent malaria, could save tens of thousands of young lives each year."
Malaria remains a primary cause of childhood illness and death in sub-Saharan Africa. More than 260, 000 African children under the age of five, die from malaria annually.
In recent years, WHO and its partners, have been reporting a stagnation in progress against the deadly disease.
"For centuries, malaria has stalked sub-Saharan Africa, causing immense personal suffering," said Dr. Matshidiso Moeti, WHO Regional Director for Africa. "We have long hoped for an effective malaria vaccine and now for the first time ever, we have such a vaccine recommended for widespread use.
Today's recommendation offers a glimmer of hope for the continent which shoulders the heaviest burden of the disease and we expect many more African children to be protected from malaria and grow into healthy adults."
WHO recommendation for the RTS,S malaria vaccine.
Based on the advice of two WHO global advisory bodies, one for immunization and the other for malaria, the Organization recommends that:
In the context of comprehensive malaria control the RTS,S/AS01 malaria vaccine be used for the prevention of P. falciparum malaria in children living in regions with moderate to high transmission as defined by WHO. RTS,S/AS01 malaria vaccine, should be provided in a schedule of 4 doses in children from 5 months of age for the reduction of malaria disease and burden.
Summary of key findings of the malaria vaccine pilots.
Key findings of the pilots informed the recommendation based on data and insights generated from two years of vaccination in child health clinics in the three pilot countries, implemented under the leadership of the Ministries of Health of Ghana, Kenya and Malawi. Findings include:
Feasible to deliver: Vaccine introduction is feasible, improves health and saves lives, with good and equitable coverage of RTS,S seen through routine immunisation systems. This occurred even in the context of the COVID-19 pandemic.
Reaching the unreached: RTS,S increases equity in access to malaria prevention.
Data from the pilot programme showed that more than two-thirds of children in the three countries who are not sleeping under a bednet are benefitting from the RTS, Svaccine Layering the tools results in over 90percent of children benefitting from at least one preventive intervention (insecticide treated bednets or the malaria vaccine).
Strong safety profile: To date, more than 2.3 million doses of the vaccine have been administered in 3 African countries – the vaccine has a favourable safety profile.
No negative impact on the uptake of bednets, other childhood vaccinations, or health-seeking behaviour for febrile illness. In areas where the vaccine has been introduced, there has been no decrease in the use of insecticide-treated nets, uptake of other childhood vaccinations or health-seeking behaviour for febrile illness.
High impact in real-life childhood vaccination settings: Significant reduction (30%) in deadly severe malaria, even when introduced in areas where insecticide-treated nets are widely used and there is good access to diagnosis and treatment.
Highly cost-effective: Modelling estimates that the vaccine is cost-effective in areas of moderate to high malaria transmission.
The next steps for the WHO-recommended malaria vaccine will include funding decisions from the global health community for broader rollout, and country decision-making on whether to adopt the vaccine as part of national malaria control strategies.
Financing for the pilot programme has been mobilised through an unprecedented collaboration among three key global health funding bodies: Gavi, the Vaccine Alliance; the Global Fund to Fight AIDS, Tuberculosis and Malaria; and Unitaid.
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